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IDH1 and IDH2 mutations in myeloid neoplasms - Novel paradigms and clinical implications
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Read the original article at Haematologica.
Published: Oct 2010, Updated: 9th Oct
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Ets-1 is a widely expressed transcription factor implicated in several biological processes including hematopoiesis, where it contributes to the regulation of cellular differentiation. The functions of Ets-1 are regulated by transcription factors as well as by phosphorylation e... Background

Cdx4 is a homeobox gene essential for normal blood formation during embryonic development in the zebrafish, through activation of posterior Hox genes. However, its role in adult mammalian hematopoiesis has not been extensively studied and its requirement in leukemia associated ...